The symptoms of an anticholinergic toxidrome include blurred vision, coma, decreased bowel sounds, delirium, dry skin, fever, flushing, hallucinations, ileus, An alternative mnemonic is DUMBELLS – Diarrhea, Urination, Miosis [ pinpoint pupils], Bradycardia [ slow heart rate ], Emesis, Lacrimation, Lethargy and Salivation.
Cholinergic crisis is the sum of symptoms of nicotinic and muscarinic effects of poisoning. The mnemonics DUMBELLS, SLUDGE and the “Killer Bees” are all used to describe the clinical manifestations (Defecation, Urination, Myosis, Muscle Weakness, Bradycardia, Bronchorrhea, Bronchospasm, Emesis, Lacrimation,
Mnemonics and phrases may help narrow the differential diagnosis when the patient has signs such as tachycardia, hyperthermia, or hypotension (Box 2) [19, 20]. Cholinergic (Examples: organophosphates, carbamates, pilocarpine). ( DUMBELLS). Diarrhea, diaphoresis. Urination. Miosis. Bradycardia, bronchosecretions.
mnemonic for the 4 pharyngeal pouches: Ear, tonsils, bottom-to-top. deck-page- img. to what lymph nodes does the prostate drain? deck-page-img. GM makes classic cars. deck-page-img. catalase pos organisms: cats Need PLACESS to Belch their Hairballs. deck-page-img. cholinergic toxicity sxs: DUMBELLS. deck- page-.
Nov 14, 2017. Anticholinesterases; Organophosphates; Sarin (nerve gas). Removed contaminated clothing if patient was exposed to insectisides; Atropine as an anti- cholinergic and combats the excess Ach; Pralidoxime if given in a timely manner regenerates acetylcholinesterase reversing the condition (timing is critical).
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In a biological warfare or bioterrorist event, the plague bacilli are inhaled as aerosol and directly result in the pneumonic plague without the involvement of bubonic. Their action on the cholinergic system at the presynaptic motor neuron terminal by blocking acetylcholine transmission across the neuromuscular junction.
Ch 14: Muscarinic Agonists and Antagonists MUSCARINIC ANTAGONISTS ( ANTICHOLINERGIC DRUGS) Prototype: Atropine Other Muscarinic Antagonists Drugs for an overactive bladder (eg, oxybutynin [Ditropan]) Scopolamine for motion sickness Ipratropium bromide (Atrovent) for COPD, rhinitis, and asthma.
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